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Oxymetazoline

Combinations ; See Below

Oxymetazoline Brands
Brand Name Manufacturer Name Distributor Drug Strength Packaging Formulation Formulation Strength Price
Nasivion Cipla Ltd. Surgipharm Ltd 0.025% 10ml Nasal spray/drops KES 120.00
Nasivion Cipla Ltd. Surgipharm Ltd 0.05% 10ml Nasal spray/drops KES 130.00
Oxylin Allergan International Ltd. Radiance Pharmaceuticals Limited 0.025% 15ml eye drops per ml KES 410.00
Utabon J. Uriach & CIA Globe Pharmacy Ltd., 0.025% 15ml Nasal spray/drops KES 178.20
Utabon J. Uriach & CIA Globe Pharmacy Ltd., 0.05% 15ml Nasal spray/drops KES 201.30

Oxymetazoline More info

Use

Adjunctive therapy for nasal congestion, associated with acute or chronic rhinitis, the common cold, sinusitis, hay fever, or other allergies

Adverse Reactions Significant

Frequency not defined.

Respiratory: Dryness of the nasal mucosa, nasal irritation (temporary), rebound congestion (chronic use), sneezing

Contraindications

Hypersensitivity to oxymetazoline or any component of the formulation

Warnings/Precautions

Concerns related to adverse effects:

• Rebound nasal congestion: May occur with extended use.

Disease-related concerns:

• Cardiovascular disease: Use with caution in patients with hypertension, heart failure, or coronary artery disease.

• Diabetes: Use with caution in patients with diabetes mellitus.

• Hyperthyroidism: Use with caution in patients with hyperthyroidism.

• Prostatic hyperplasia: Use with caution in patients with benign prostatic hyperplasia.

Drug Interactions

(For additional information: Launch Lexi-Interact™ Drug Interactions Program )

Atomoxetine: May enhance the hypertensive effect of Sympathomimetics. Atomoxetine may enhance the tachycardic effect of Sympathomimetics. Risk C: Monitor therapy

Cannabinoids: May enhance the tachycardic effect of Sympathomimetics. Risk C: Monitor therapy

Iobenguane I 123: Sympathomimetics may diminish the therapeutic effect of Iobenguane I 123. Risk X: Avoid combination

MAO Inhibitors: May enhance the hypertensive effect of Alpha1-Agonists. Risk X: Avoid combination

Sympathomimetics: May enhance the adverse/toxic effect of other Sympathomimetics. Risk C: Monitor therapy

Tricyclic Antidepressants: May enhance the vasopressor effect of Alpha1-Agonists. Risk D: Consider therapy modification

Pregnancy Implications

Adverse fetal or neonatal effects have not been observed following normal maternal doses of oxymetazoline during the third trimester of pregnancy. Adverse events have been noted in case reports following large doses or extended use. Decongestants are not the preferred agents for the treatment of rhinitis during pregnancy. Short-term (<3 days) use of intranasal oxymetazoline may be beneficial to some patients although its safety during pregnancy has not been studied